Efficacy and safety of alirocumab in patients with established atherosclerotic vascular disease before the first cardiovascular event: Pooled analysis of phase 3 ODYSSEY studies

Among patients with ASCVD without previous ACS or stroke, alirocumab significantly reduced calculated LDL-C levels vs controls and was well tolerated.

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Publication Details

Journal
Journal of clinical lipidology
Published
2025-10-23
DOI
https://doi.org/10.1016/j.jacl.2025.10.062
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
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article

Efficacy and safety of alirocumab in patients with established atherosclerotic vascular disease before the first cardiovascular event: Pooled analysis of phase 3 ODYSSEY studies

Deepak L. Bhatt, José Tuñón, Hagai Tavori, Michal Vráblík et al.
Journal of clinical lipidology
Lipoproteins and Cardiovascular Health
article

Efficacy and safety of alirocumab in patients with established atherosclerotic vascular disease before the first cardiovascular event: Pooled analysis of phase 3 ODYSSEY studies

Deepak L. Bhatt, José Tuñón, Hagai Tavori, Michal Vráblík, Pasquale Perrone Filardi, Manuel Castro Cabezas, Nikolaus Marx, Mattéa Orsini, Lâle Tokgözoğlu
article en

Abstract

Among patients with ASCVD without previous ACS or stroke, alirocumab significantly reduced calculated LDL-C levels vs controls and was well tolerated.

Journal of clinical lipidologyVol. 20(1)
SANE Mental Health Charity (GB), Charles University (CZ), Sint Franciscus Gasthuis (NL), Mount Sinai Hospital (US), CIEP (FR), Federico II University Hospital (IT), Hospital Universitario Fundación Jiménez Díaz (ES), Westfälische Hochschule (DE), General University Hospital in Prague (CZ), Hacettepe University (TR)
Openalex Percentile: Top 52%
Lipoproteins and Cardiovascular Health
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Efficacy and safety of alirocumab in patients with established atherosclerotic vascular disease before the first cardiovascular event: Pooled analysis of phase 3 ODYSSEY studies — Deepak L. Bhatt, José Tuñón, et al. · Journal of clinical lipidology (2025) | TGRS Research Map | TGRS