Jugular bulb venous to arterial carbon dioxide gradient is associated with treatment-responsive phenotypes of hypoxic-ischemic brain injury
When interpreted with SjvO<sub>2</sub>, the cerebral pCO<sub>2</sub> gap may uncover covert cerebral dysfunction, and can identify treatment-responsive causes of elevated SjvO<sub>2</sub>. Thus, the pCO<sub>2</sub> gap may be a useful adjunct for phenotyping HIBI.
Authors
- Hernando Gómez (ORCID: https://orcid.org/0000-0001-5605-3513)
- Jonathan Elmer (ORCID: https://orcid.org/0000-0002-6648-5456)
- Cecelia Ratay (ORCID: https://orcid.org/0000-0002-8813-9327)
- Ankur Doshi (ORCID: https://orcid.org/0000-0003-2040-4179)
- Clifton W. Callaway (ORCID: https://orcid.org/0000-0002-3309-1573)
- Joseph Mettenburg
- Byron C. Drumheller (ORCID: https://orcid.org/0000-0002-0960-4412)
- Francis Xavier Guyette (ORCID: https://orcid.org/0000-0002-9151-4896)
- Masashi Okubo (ORCID: https://orcid.org/0000-0002-1447-8908)
- Alexis Steinberg (ORCID: https://orcid.org/0000-0002-6681-9380)
- Joanna S. Fong-Isariyawongse (ORCID: https://orcid.org/0000-0002-6847-6166)
- Joseph M. Darby (ORCID: https://orcid.org/0000-0001-5404-2343)
- Katharyn L. Flickinger (ORCID: https://orcid.org/0000-0002-7631-1687)
- Laura Faiver (ORCID: https://orcid.org/0000-0001-5454-4773)
- Jonathan Tam (ORCID: https://orcid.org/0009-0006-0375-0394)
- Alexandra Weissman
Institutions
- University of Pittsburgh (US)
Publication Details
- Journal
- Resuscitation Plus
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1016/j.resplu.2025.101136
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00