MON-214 Impact of Type 1 Diabetes on Growth in Korean Pediatric Patients: A Comparative Analysis of Final Adult Height and Parental Height

Abstract Disclosure: M. Cho: None. Y. Shim: None. H. Lee: None. Abstract Purpose: Chronic metabolic disorders have been shown to impact the growth and development of pediatric and adolescent patients. The aim of this study is to analyze the impact of type 1 diabetes on growth by comparing the final adult height of the patients to the heights of their parents. Methods: We retrospectively analyzed the medical records of 91 patients who were diagnosed with Type 1 Diabetes at Ajou University Hospital in Suwon, Korea at least one year before the completion of their linear growth and who continued receiving care this hospital until they reached their final adult height. Results: The average age at diagnosis for the 91 patients was 10.82 ± 3.32 years, with 49 (53.8%) being male. At diagnosis, the mean HbA1c level was 12.39 ± 1.90%, and the average duration of diabetes was 5.18 ± 3.27 years. Analysis of height growth in the study participants revealed that the height SDS at diagnosis was 0.21 ± 1.25, while the final adult height SDS was -0.13 ± 1.17. When comparing the final adult height (FAH) of the patients to the mean parental height (MPH), the FAH-MPH SDS was -0.11 ± 0.98, indicating that the final adult height of children with type 1 diabetes was somewhat smaller than expected. Multiple regression analysis showed that a greater height at diagnosis, shorter parental height, and shorter duration of diabetes were associated with a final adult height (FAH) greater than the mean parental height (MPH). The average level of blood glucose control did not have a statistically significant effect. Conclusions: This study confirms that a longer diabetic duration is associated with a smaller final adult height than expected. It highlights the importance of not only managing blood glucose levels but also paying attention to height growth when treating children diagnosed at a young age. Presentation: Monday, July 14, 2025