Nasal hamartomas: a case series and literature review

Abstract BACKGROUND. Nasal and nasopharyngeal hamartomas are rare, benign developmental lesions that often mimic other sinonasal pathologies. Misdiagnosis may lead to unnecessary interventions. OBJECTIVE. To present a case series involving three histological subtypes of nasal hamartomas and to review the current understanding regarding their classification, diagnosis, and management. MATERIAL AND METHODS. We describe three patients treated at our institution, each with a distinct subtype of nasal hamartoma: respiratory epithelial adenomatoid hamartoma (REAH), seromucinous hamartoma (SH), and nasal chondromesenchymal hamartoma (NCMH). Clinical, radiological, surgical, and histological data were analyzed. RESULTS. All patients underwent successful endoscopic surgical excision. Postoperative outcomes were favorable with no recurrence during followup. Histological analysis confirmed the diagnosis in each case. CONCLUSION. Nasal hamartomas, though rare, should be included in the differential diagnosis of sinonasal masses. Accurate diagnosis relies on histopathology, and complete surgical excision leads to excellent prognosis.