Epidemiology of Lower Extremity Amputations in the United States: An Analysis of the Global Burden of Disease Database From 1990 to 2019
From 1990 to 2019, the US experienced decreases in YLDs, prevalence, and incidence of unilateral and bilateral LEAs, except for an increased incidence of unilateral LEAs. Men experienced higher rates than women across each region. The West generally had the highest overall rates. These trends highlight sex-specific and regional disparities of LEAs.
Authors
- Cameron John Sabet (ORCID: https://orcid.org/0000-0003-2299-1426)
- Taylor J. Manes (ORCID: https://orcid.org/0000-0002-6622-060X)
- Jack W. Weick (ORCID: https://orcid.org/0000-0003-3344-4727)
- Peter Spencer (ORCID: https://orcid.org/0000-0002-8538-1695)
- Phillip C. McKegg
- Gabrielle Dykhouse (ORCID: https://orcid.org/0009-0003-5756-7737)
- A. Ibrahim (ORCID: https://orcid.org/0000-0003-2019-0385)
- Ambrose Loc T Ngo (ORCID: https://orcid.org/0009-0002-6993-9131)
Institutions
- Philadelphia College of Osteopathic Medicine (US)
- OhioHealth (US)
- Grant Medical Center (US)
- Kansas City University (US)
- Georgetown University (US)
- Cornell University (US)
- Heritage College (CA)
- Henry Ford Hospital (US)
- Ohio University (US)
Publication Details
- Journal
- Cureus
- Published
- 2025-10-22
- DOI
- https://doi.org/10.7759/cureus.95188
- Primary Topic
- Diabetic Foot Ulcer Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00