Comparison of Preoperative Subconjunctival Injection, Intraoperative Subconjunctival Injection, and Soaked Sponges as Mitomycin C Delivery Methods for Trabeculectomy with a 6-Month Follow-Up Period: A Randomized Controlled Pilot Study
In this pilot study, all MMC delivery methods demonstrated comparable success rates, IOP reduction, and safety outcomes. Subconjunctival MMC injections show promise as a viable alternative to the conventional sponge application. However, due to the small sample size, further larger-scale studies are warranted to validate these findings.
Authors
- Tharnsook Kasemsup
- Nopphawan Uramphorn
- Pradtana Hirunpatravong (ORCID: https://orcid.org/0000-0002-4624-5367)
- Joseph Caprioli (ORCID: https://orcid.org/0000-0002-2383-7263)
Institutions
- Navamindradhiraj University (TH)
- Vajira Hospital (TH)
- Doheny Eye Institute (US)
Publication Details
- Journal
- Journal of Ocular Pharmacology and Therapeutics
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1177/10807683251391092
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00