Comparison of Preoperative Subconjunctival Injection, Intraoperative Subconjunctival Injection, and Soaked Sponges as Mitomycin C Delivery Methods for Trabeculectomy with a 6-Month Follow-Up Period: A Randomized Controlled Pilot Study

In this pilot study, all MMC delivery methods demonstrated comparable success rates, IOP reduction, and safety outcomes. Subconjunctival MMC injections show promise as a viable alternative to the conventional sponge application. However, due to the small sample size, further larger-scale studies are warranted to validate these findings.

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Publication Details

Journal
Journal of Ocular Pharmacology and Therapeutics
Published
2025-10-23
DOI
https://doi.org/10.1177/10807683251391092
Primary Topic
Glaucoma and retinal disorders
Type
article
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article

Comparison of Preoperative Subconjunctival Injection, Intraoperative Subconjunctival Injection, and Soaked Sponges as Mitomycin C Delivery Methods for Trabeculectomy with a 6-Month Follow-Up Period: A Randomized Controlled Pilot Study

Tharnsook Kasemsup, Nopphawan Uramphorn, Pradtana Hirunpatravong, Joseph Caprioli
Journal of Ocular Pharmacology and Therapeutics
Glaucoma and retinal disorders
article

Comparison of Preoperative Subconjunctival Injection, Intraoperative Subconjunctival Injection, and Soaked Sponges as Mitomycin C Delivery Methods for Trabeculectomy with a 6-Month Follow-Up Period: A Randomized Controlled Pilot Study

Tharnsook Kasemsup, Nopphawan Uramphorn, Pradtana Hirunpatravong, Joseph Caprioli
article en

Abstract

In this pilot study, all MMC delivery methods demonstrated comparable success rates, IOP reduction, and safety outcomes. Subconjunctival MMC injections show promise as a viable alternative to the conventional sponge application. However, due to the small sample size, further larger-scale studies are warranted to validate these findings.

Journal of Ocular Pharmacology and Therapeutics
Navamindradhiraj University (TH), Vajira Hospital (TH), Doheny Eye Institute (US)
Openalex Percentile: Top 56%
Glaucoma and retinal disorders
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Comparison of Preoperative Subconjunctival Injection, Intraoperative Subconjunctival Injection, and Soaked Sponges as Mitomycin C Delivery Methods for Trabeculectomy with a 6-Month Follow-Up Period: A Randomized Controlled Pilot Study — Tharnsook Kasemsup, Nopphawan Uramphorn, et al. · Journal of Ocular Pharmacology and Therapeutics (2025) | TGRS Research Map | TGRS