Post-marketing Surveillance of Intranasal Nalmefene: Prevalence and Clinical Relevance of Precipitated Withdrawal
Post-marketing surveillance data suggest that the risk of precipitated withdrawal with IN nalmefene is low in real-world settings. These findings support the continued deployment of IN nalmefene as a life-saving intervention while underscoring the importance of ongoing pharmacovigilance to monitor for emerging safety signals.
Authors
- Baher Mankabady
- Céline M. Laffont (ORCID: https://orcid.org/0000-0001-8345-5980)
- Phil Skolnick (ORCID: https://orcid.org/0000-0002-2646-815X)
- Christian Heidbreder (ORCID: https://orcid.org/0000-0001-8937-003X)
- Ann P. Wheeler (ORCID: https://orcid.org/0009-0007-2979-0308)
- Jordan Paavola
Institutions
- Indivior (United States) (US)
Publication Details
- Journal
- Cureus
- Published
- 2025-10-22
- DOI
- https://doi.org/10.7759/cureus.95174
- Primary Topic
- Dental Anxiety and Anesthesia Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00