Development and Validation of an Extra Spindle Pole Bodies–like 1–Based Diagnostic and Prognostic Model for Hepatitis B Virus–Related Hepatocellular Carcinoma: Retrospective Cohort Study
The ESPL1-based model may serve as both a diagnostic tool for differentiating patients with HCC from those with non-HCC and as a preliminary approach for risk stratification during follow-up. This dual role has the potential to support earlier detection and personalized monitoring. The web-based calculator improves accessibility and may facilitate future clinical integration.
Authors
- Minghua Su (ORCID: https://orcid.org/0000-0001-7831-6580)
- Haiping Liang (ORCID: https://orcid.org/0009-0000-6225-3394)
- Jianning Jiang (ORCID: https://orcid.org/0009-0005-1354-5127)
- Hengkai Liang
- Lu-Huai Feng (ORCID: https://orcid.org/0000-0002-1715-4028)
- Bobin Hu (ORCID: https://orcid.org/0009-0008-4710-775X)
- Yanfei Feng
- Lu Wei
- Qianbing Yin
- Tumei Su
- Qingmei Li
- Linxian Huang
Institutions
- Guangxi University (CN)
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Guangxi Center for Disease Prevention and Control (CN)
Publication Details
- Journal
- JMIR Medical Informatics
- Published
- 2025-10-22
- DOI
- https://doi.org/10.2196/78354
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00