Combined Influence of Dental Caries and Periodontal Disease on Ischemic Stroke Risk
Periodontal disease (PD) and dental caries are prevalent chronic oral inflammatory conditions associated with systemic health outcomes. Individually, both have been linked to an increased risk of ischemic stroke, a leading cause of morbidity and mortality. However, few studies have examined the combined effect of PD and dental caries on stroke, stroke subtypes, and major adverse cardiovascular events (MACEs) within US cohorts. We aimed to evaluate the individual and joint associations of PD and dental caries with incident ischemic stroke, stroke subtypes, and MACEs and assess the relationship between regular dental care utilization and oral disease status.
Authors
- Jaclyn Meyer (ORCID: https://orcid.org/0000-0001-9910-8086)
- Souvik Sen (ORCID: https://orcid.org/0000-0002-0886-2364)
- Kevin Moss (ORCID: https://orcid.org/0000-0003-2332-1774)
- Wayne D. Rosamond (ORCID: https://orcid.org/0000-0001-5271-074X)
- James D. Beck (ORCID: https://orcid.org/0000-0001-5415-8311)
- Scott J. Wood (ORCID: https://orcid.org/0000-0002-2603-7552)
- Michelle C. Johansen (ORCID: https://orcid.org/0000-0003-0393-3589)
- Lawson Logue
Institutions
- University of North Carolina at Chapel Hill (US)
- Johns Hopkins University (US)
- University of South Carolina (US)
- Johns Hopkins Medicine (US)
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Neurology Open Access
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1212/wn9.0000000000000036
- Citations
- 1
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 1.47