Multitask Language Mapping to Visualize the Spatial Configuration of Polyfunctional Language Cortex
Multitask DES anchored to the YBA provides an anatomically precise, reproducible platform for language mapping. A focused task set enhances efficiency without sacrificing sensitivity. Integration with structural connectivity offers network-level insights. Limitations include modest sample size, variable electrode coverage with undersampling of the anterior language areas, and patient population with epilepsy, which may affect generalizability. This multimodal framework informs surgical planning and advances our understanding of human language representation.
Authors
- Hari McGrath (ORCID: https://orcid.org/0000-0002-0037-4761)
- Eyiyemisi C. Damisah (ORCID: https://orcid.org/0000-0001-8854-1335)
- Evan Collins (ORCID: https://orcid.org/0000-0003-0774-6975)
- Omar Chishti (ORCID: https://orcid.org/0000-0003-1789-0030)
- Christopher Benjamin (ORCID: https://orcid.org/0000-0002-2000-9016)
- Imran H. Quraishi (ORCID: https://orcid.org/0000-0003-2859-7446)
- Hitten P. Zaveri (ORCID: https://orcid.org/0000-0001-7830-0052)
- Adithya Sivaraju (ORCID: https://orcid.org/0000-0002-6027-9205)
- Tiffany Zhang
- Lawrence J. Hirsch (ORCID: https://orcid.org/0000-0002-6333-832X)
- Dennis D. Spencer (ORCID: https://orcid.org/0000-0002-1716-9887)
- Ryan Bose-Roy
Institutions
- Yale New Haven Hospital (US)
- Vancouver General Hospital (CA)
- Yale University (US)
- Yale New Haven Health System (US)
- King's College School (GB)
- Max Planck Institute for Human Cognitive and Brain Sciences (DE)
- Massachusetts Institute of Technology (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1212/wnl.0000000000214256
- Citations
- 1
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.43