Interaction of potato-derived RG-I with galectin-3 and gene regulation in human mesenchymal stem cells
This study indicates that modified potato pectin (PA) can regulate the expression of a broad range of genes, including galectin-3, that are involved in cellular, inflammatory, and immunological functions of hMSCs and may potentially be used to promote bone regeneration via modulation of inflammation.
Authors
- Athina Giannoudis (ORCID: https://orcid.org/0000-0002-7200-1497)
- Bodil Jørgensen (ORCID: https://orcid.org/0000-0002-0453-1277)
- Oluwatobi Samuel Adegbite (ORCID: https://orcid.org/0000-0002-1731-6883)
- Katarzyna Gurzawska (ORCID: https://orcid.org/0000-0002-3424-5968)
- Anna Mieszkowska (ORCID: https://orcid.org/0000-0003-1152-9789)
- Xuan Liu (ORCID: https://orcid.org/0009-0009-5004-2616)
- Dong‐Mei Wu (ORCID: https://orcid.org/0000-0002-1816-1107)
- Lugang Yu
- A. Mukhtar
- Kamal Mustafa (ORCID: https://orcid.org/0009-0008-5492-1493)
- Gudveig Cecilie Gjerde Gjengedal
Institutions
- University of Copenhagen (DK)
- Jagiellonian University (PL)
- University of Liverpool (GB)
- Aarhus University (DK)
- Aarhus University Hospital (DK)
- Yale University (US)
- University of Bergen (NO)
Publication Details
- Journal
- BMC Biotechnology
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1186/s12896-025-01030-z
- Primary Topic
- Galectins and Cancer Biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00