Evaluation of Articular Cartilage in Knee Osteoarthritis Using Macromolecular Proton Fraction Mapping
Macromolecular proton fraction mapping demonstrated sensitivity to early-stage cartilage degeneration in osteoarthritis, suggesting its potential as a biomarker for early osteoarthritis detection. The combination of macromolecular proton fraction and T<sub>2</sub>* mapping could enhance the biochemical assessment of cartilage integrity, providing valuable insights for early diagnosis and monitoring treatment effects in osteoarthritis.
Authors
- Motohira Mio (ORCID: https://orcid.org/0000-0002-1517-3348)
- Yasuhiro Fujiwara (ORCID: https://orcid.org/0000-0002-1229-5446)
- Mika Kitajima
- Kosuke Yamashita (ORCID: https://orcid.org/0000-0003-0133-7441)
- Mio Ariki
Institutions
- Kumamoto Health Science University (JP)
- Fukuoka University (JP)
- Fukuoka University Tsukushi Hospital (JP)
- Kumamoto University (JP)
Publication Details
- Journal
- Magnetic Resonance in Medical Sciences
- Published
- 2025-10-22
- DOI
- https://doi.org/10.2463/mrms.mp.2025-0053
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00