Therapeutic value of dissecting stations 1 and 4Sb lymph nodes during radical distal gastrectomy for lower- and middle-third gastric cancer
Routine dissection of station 4Sb LNs in LGC offers negligible survival benefit. Furthermore, given that station 1 metastasis is not an independent prognostic factor in LGC, its routine dissection also warrants reconsideration. These findings support a biology-driven refinement of lymphadenectomy guidelines, suggesting that omitting station 4Sb and selectively omitting station 1 in LGC may be oncologically safe. Prospective validation is crucial.
Authors
- Ren-hao Hu
- Shun Zhang (ORCID: https://orcid.org/0000-0002-3493-1247)
- Peng Liao (ORCID: https://orcid.org/0000-0001-5740-7272)
- Ximao Cui (ORCID: https://orcid.org/0000-0002-9871-9878)
- Xiaohua Jiang (ORCID: https://orcid.org/0000-0001-7001-4676)
Institutions
- Tongji University (CN)
- Shanghai East Hospital (CN)
Publication Details
- Journal
- World Journal of Surgical Oncology
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1186/s12957-025-04054-z
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00