Therapeutic value of dissecting stations 1 and 4Sb lymph nodes during radical distal gastrectomy for lower- and middle-third gastric cancer

Routine dissection of station 4Sb LNs in LGC offers negligible survival benefit. Furthermore, given that station 1 metastasis is not an independent prognostic factor in LGC, its routine dissection also warrants reconsideration. These findings support a biology-driven refinement of lymphadenectomy guidelines, suggesting that omitting station 4Sb and selectively omitting station 1 in LGC may be oncologically safe. Prospective validation is crucial.

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Publication Details

Journal
World Journal of Surgical Oncology
Published
2025-10-22
DOI
https://doi.org/10.1186/s12957-025-04054-z
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Therapeutic value of dissecting stations 1 and 4Sb lymph nodes during radical distal gastrectomy for lower- and middle-third gastric cancer

Ren-hao Hu, Shun Zhang, Peng Liao, Ximao Cui et al.
World Journal of Surgical Oncology
Gastric Cancer Management and Outcomes
article

Therapeutic value of dissecting stations 1 and 4Sb lymph nodes during radical distal gastrectomy for lower- and middle-third gastric cancer

Ren-hao Hu, Shun Zhang, Peng Liao, Ximao Cui, Xiaohua Jiang
article en

Abstract

Routine dissection of station 4Sb LNs in LGC offers negligible survival benefit. Furthermore, given that station 1 metastasis is not an independent prognostic factor in LGC, its routine dissection also warrants reconsideration. These findings support a biology-driven refinement of lymphadenectomy guidelines, suggesting that omitting station 4Sb and selectively omitting station 1 in LGC may be oncologically safe. Prospective validation is crucial.

World Journal of Surgical OncologyVol. 23(1)
Tongji University (CN), Shanghai East Hospital (CN)
Openalex Percentile: Top 57%
Gastric Cancer Management and Outcomes
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