The Association Between Frailty, Pao 2/Fio 2 Ratio, and Hospital Mortality: A Retrospective Registry-Based Cohort Study
This multicenter, retrospective study that investigated the association between frailty, AHRF, and in-hospital mortality found that AHRF was highly prevalent in patients with frailty. Increasing frailty was associated with higher in-hospital mortality in AHRF and its increasing severity, with a nonlinear relationship.
Authors
- Aidan Burrell (ORCID: https://orcid.org/0000-0001-8430-9678)
- Ashwin Subramaniam (ORCID: https://orcid.org/0000-0002-8292-7357)
- Kiran Shekar (ORCID: https://orcid.org/0000-0002-1239-7514)
- Benjamin Moran (ORCID: https://orcid.org/0000-0002-6515-6722)
- DAVID B. PILCHER
- Mahesh Ramanan (ORCID: https://orcid.org/0000-0003-4509-4015)
- Ryan Ruiyang Ling (ORCID: https://orcid.org/0000-0002-8335-7640)
- Mallikarjuna Ponnapa Reddy (ORCID: https://orcid.org/0000-0002-4736-2901)
- Kollengode Ramanathan
Institutions
- Bond University (AU)
- The University of Queensland (AU)
- National University of Singapore (SG)
- Epworth Hospital (AU)
- Gosford Hospital (AU)
- Nepean Hospital (AU)
- The Alfred Hospital (AU)
- Khoo Teck Puat Hospital (SG)
- Canberra Hospital (AU)
- UNSW Sydney (AU)
- Australian and New Zealand Intensive Care Society (AU)
- National University Heart Centre Singapore (SG)
- The George Institute for Global Health (AU)
- Peninsula Health (AU)
- Monash Health (AU)
- Prince Charles Hospital (AU)
- Dandenong Hospital (AU)
- Monash University (AU)
- University of Newcastle Australia (AU)
Publication Details
- Journal
- Critical Care Medicine
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1097/ccm.0000000000006917
- Citations
- 2
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 2.45