Predictors of acute upper GI toxicity and its correlation with dosimetric analysis in patients receiving adjuvant radiation therapy for breast cancer
Radiation technique, dose-volume parameters and breathing strategy significantly influence acute upper GI toxicity and dysphagia in breast cancer RT. DIBH reduces GI toxicity risk, while higher stomach and esophageal doses correlate with increased toxicity. Incorporating the stomach as an OAR and optimising treatment planning can enhance tolerability and improve patient outcomes.
Authors
- Nawazish Zehra
- Maria Tariq
- Sehrish Abrar
- Bilal Ahmed (ORCID: https://orcid.org/0000-0003-1013-8663)
- Maham Khan
- Mariam Hina (ORCID: https://orcid.org/0000-0003-3386-772X)
- Laraib Khan
- Tooba Ali (ORCID: https://orcid.org/0000-0002-4279-2224)
- Ahmed Nadeem Abbasi (ORCID: https://orcid.org/0000-0002-9314-4059)
- Syed K. Hasan (ORCID: https://orcid.org/0000-0001-9580-5183)
- Nasir Ali (ORCID: https://orcid.org/0000-0003-4502-8720)
- Fabiha Shakeel
- Asim Hafiz
- Bilal Mazhar Qureshi
Institutions
- Aga Khan University (PK)
- Sindh Institute of Urology and Transplantation (PK)
Publication Details
- Journal
- ecancermedicalscience
- Published
- 2025-10-22
- DOI
- https://doi.org/10.3332/ecancer.2025.2020
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00