tNGS Reveals Predominant Mixed Viral Infections in a Multicenter Retrospective Study
Targeted next-generation sequencing identified a higher prevalence and broader spectrum of viral co-infections and secondary bacterial/fungal infections compared with conventional methods. These findings highlight the complexity of respiratory infections in the post-COVID-19 era and support the potential of tNGS as a comprehensive diagnostic approach in clinical practice.
Authors
- Rui Tang (ORCID: https://orcid.org/0000-0002-8524-771X)
- Xiaoqi Zhang
- Lijuan Li (ORCID: https://orcid.org/0000-0001-5984-1603)
- Xiaoyan Li (ORCID: https://orcid.org/0000-0001-7166-0135)
Institutions
- China-Japan Friendship Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Tangshan People's Hospital (CN)
- Weifang People's Hospital (CN)
- People's Hospital of Cangzhou (CN)
- Tangshan Gongren Hospital (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/idr.s544262
- Citations
- 1
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- China-Japan Friendship Hospital