Preservation of Platelet Function After Intraoperative Cell Salvage Using the i-SEP Same Device in Cardiac Surgery
The Same device enabled recovery of functional platelets and red blood cells from cardiopulmonary bypass blood. Based on the estimated equivalent yield per processing cycle, the cumulative platelet recovery over three cycles corresponded to approximately one-third of the platelet count of a standard platelet concentrate. This suggests a potentially significant contribution of autologous platelet recovery to perioperative hemostatic support, although the clinical significance of this finding warrants further investigation.
Authors
- Benjamin Friedrichson (ORCID: https://orcid.org/0000-0003-3790-281X)
- Sonja Iken
- Kai Zacharowski (ORCID: https://orcid.org/0000-0002-0212-9110)
- Michael Nordine (ORCID: https://orcid.org/0000-0002-5510-0776)
- Ulrike Heinicke
- Lea Valeska Blum
- Florian Hecker
- Gösta Lotz (ORCID: https://orcid.org/0000-0003-2291-5159)
- J. Rausch (ORCID: https://orcid.org/0009-0004-6296-8663)
- Andreas von Knethen (ORCID: https://orcid.org/0000-0002-5831-0365)
- Fadime Sertdere
Institutions
- Goethe University Frankfurt (DE)
- University Hospital Frankfurt (DE)
Publication Details
- Journal
- Journal of Cardiothoracic and Vascular Anesthesia
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1053/j.jvca.2025.10.024
- Citations
- 1
- Primary Topic
- Cardiac and Coronary Surgery Techniques
- Type
- article
- Field-Weighted Citation Impact
- 2.01