Different measures of sodium intake and the risk of metabolic dysfunction-associated steatotic liver disease: Evidence from the UK Biobank

The habit of always adding salt to food, a 24-h urinary sodium excretion above 1.93 g/day, and energy-adjusted dietary sodium intake above 1.49g/d increased the risk of MASLD, partly mediated through inflammation, insulin resistance, and renal dysfunction. It is recommended that public health strategies target reducing MASLD risk based on these findings.

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Publication Details

Journal
Annals of Hepatology
Published
2025-10-22
DOI
https://doi.org/10.1016/j.aohep.2025.102145
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Different measures of sodium intake and the risk of metabolic dysfunction-associated steatotic liver disease: Evidence from the UK Biobank

Lu Liu, Jiaxi Lin, Jinzhou Zhu, Shiqi Zhu et al.
Annals of Hepatology
Liver Disease Diagnosis and Treatment
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Different measures of sodium intake and the risk of metabolic dysfunction-associated steatotic liver disease: Evidence from the UK Biobank

Lu Liu, Jiaxi Lin, Jinzhou Zhu, Shiqi Zhu, Yiping Shen, Hongpeng Sun, Lihe Liu, Xiaolin Liu, Rui Li
article en

Abstract

The habit of always adding salt to food, a 24-h urinary sodium excretion above 1.93 g/day, and energy-adjusted dietary sodium intake above 1.49g/d increased the risk of MASLD, partly mediated through inflammation, insulin resistance, and renal dysfunction. It is recommended that public health strategies target reducing MASLD risk based on these findings.

Annals of HepatologyVol. 31(1)
Soochow University (CN), First Affiliated Hospital of Soochow University (CN)
Openalex Percentile: Top 60%
Liver Disease Diagnosis and Treatment
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