Prenatal and Early Postnatal Lead Exposure, Sensitive Periods, and Later Adult Mental Health
Third-trimester lead exposure was associated with higher risk of major depressive disorder and anxiety symptoms in later adulthood. These findings emphasize the importance of factoring in later life health outcomes when considering the benefits of lead exposure interventions in childhood and suggest investment in screening and mental health services may be needed to address the long-term burden of historical lead exposure.
Authors
- Ruby Hickman (ORCID: https://orcid.org/0000-0003-2856-9509)
- Scott M. Bartell (ORCID: https://orcid.org/0000-0001-7797-2906)
- Ian W. Tang (ORCID: https://orcid.org/0000-0002-0775-891X)
- Felicitas B. Bidlack (ORCID: https://orcid.org/0000-0001-8105-223X)
- Brian P. Jackson (ORCID: https://orcid.org/0000-0003-2311-2972)
- Joseph J. Mangano (ORCID: https://orcid.org/0000-0001-7610-7638)
- Michael C.M. Leung (ORCID: https://orcid.org/0000-0003-4831-9566)
- Joyce J. Y. Lin (ORCID: https://orcid.org/0000-0001-8382-1020)
- Tracy Punshon (ORCID: https://orcid.org/0000-0003-0782-446X)
- Marc G. Weisskopf (ORCID: https://orcid.org/0000-0003-4513-9834)
- Kaleigh McAlaine
- Justin G. Farmer
Institutions
- Dartmouth College (US)
- Harvard University (US)
- International Craniofacial Institute (US)
- Faculty of Public Health (GB)
- Public Health Solutions (US)
Publication Details
- Journal
- JAMA Psychiatry
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1001/jamapsychiatry.2025.3012
- Citations
- 1
- Primary Topic
- Heavy Metal Exposure and Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 1.20