Trial Enrollment and Survival Disparities Among Patients With Advanced Epithelial Ovarian Carcinoma
In this cohort study, Black and Asian patients were underrepresented in RCT trial populations. Black patients had lower OS than White and Asian patients but similar PFS. Equitable enrollment in clinical trials ensures access to cutting-edge treatments and can lead to outcomes comparable to those of White counterparts. Sustained efforts to improve RCT diversity remain essential to long-term equity in cancer care and survival.
Authors
- John K. C. Chan (ORCID: https://orcid.org/0000-0001-5068-6707)
- Alex Francoeur (ORCID: https://orcid.org/0000-0001-8606-6817)
- Natalie L. Ayoub (ORCID: https://orcid.org/0000-0003-2931-5834)
- Michael Richardson (ORCID: https://orcid.org/0000-0002-3011-1591)
- Caitlin Ruth Johnson
- Amandeep Mann (ORCID: https://orcid.org/0000-0002-9470-4839)
- Kathleen M. Darcy (ORCID: https://orcid.org/0000-0003-2888-2968)
- Chunqiao Tian (ORCID: https://orcid.org/0000-0003-3815-8025)
- D.S. Kapp
Institutions
- Sutter Health (US)
- Henry M. Jackson Foundation (US)
- University of California, Los Angeles (US)
- University of California, Irvine (US)
- Walter Reed National Military Medical Center (US)
- Stanford University (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.38648
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00