Screening and regulatory mechanisms of biomarkers related to neddylation in laryngeal squamous cell carcinoma

This study successfully established a neddylation-associated prognostic risk model for LSCC and revealed that COMMD2, WSB2, and CUL9 could act as new therapeutic targets, which might provide valuable information for the research and treatment of LSCC.

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Publication Details

Journal
Frontiers in Molecular Biosciences
Published
2025-10-22
DOI
https://doi.org/10.3389/fmolb.2025.1654064
Primary Topic
Cancer-related gene regulation
Type
article
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article

Screening and regulatory mechanisms of biomarkers related to neddylation in laryngeal squamous cell carcinoma

Haixiang Zhang, Xin Wang, Jinping Wang
Frontiers in Molecular Biosciences
Cancer-related gene regulation
article

Screening and regulatory mechanisms of biomarkers related to neddylation in laryngeal squamous cell carcinoma

Haixiang Zhang, Xin Wang, Jinping Wang
article en

Abstract

This study successfully established a neddylation-associated prognostic risk model for LSCC and revealed that COMMD2, WSB2, and CUL9 could act as new therapeutic targets, which might provide valuable information for the research and treatment of LSCC.

Frontiers in Molecular BiosciencesVol. 12
Shanxi Medical University (CN), Shaanxi Provincial People's Hospital (CN), Shanxi Provincial People’s Hospital (CN)
Openalex Percentile: Top 73%
Cancer-related gene regulation
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