Biomechanical Impact of Partitioning Position and Angle on Post‐SPGJ Gastric Emptying
Stomach-partitioning gastrojejunostomy (SPGJ) improves gastric-outlet obstruction outcomes, yet its biomechanical basis and geometric optimization remain unclear. Patient computed tomography (CT) data were used to reconstruct realistic SPGJ models. Computational fluid dynamics combined with a discrete phase model quantified velocity, wall pressure, particle-retention time, and velocity under systematic variations of partitioning position (distal, mid, and proximal), partitioning angle (5°, 15°, and 25°; left- or right-sided), and incision angle (60°, 75°, and 90°). Distal partitioning produced the lowest pressure drop and fastest emptying, whereas proximal partitioning channeled high-speed flow toward the pylorus and prolonged retention. A ∼15° partitioning angle balanced flow restriction and clearance; extreme unilateral angles either increased particle stasis (left-side) or slowed emptying despite reduced reflux (right-side). A vertical incision (90°) further decreased pressure losses and shortened mean retention relative to oblique cuts. SPGJ biomechanics are highly geometry-sensitive. Distal placement, a 15° partitioning angle, and a near-vertical incision collectively optimize flow, reduce lesion contact, and accelerate gastric emptying, providing quantitative guidance for patient-specific SPGJ design.
Authors
- Qiuliang Li
- Haiqiao Zhang (ORCID: https://orcid.org/0000-0003-1387-6995)
- Xia Ye (ORCID: https://orcid.org/0000-0002-4178-4783)
- Jun Zhang (ORCID: https://orcid.org/0000-0001-5411-1273)
- Fengyan Xu (ORCID: https://orcid.org/0000-0003-1063-3592)
- Zhi Zheng (ORCID: https://orcid.org/0000-0002-1787-7875)
- Zhenmin Fan (ORCID: https://orcid.org/0000-0001-9769-8107)
Institutions
- Capital Medical University (CN)
- Jiangsu University of Technology (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- Annals of the New York Academy of Sciences
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1111/nyas.70104
- Primary Topic
- Esophageal and GI Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Beijing Municipal Administration of Hospitals