Biomechanical Impact of Partitioning Position and Angle on Post‐SPGJ Gastric Emptying

Stomach-partitioning gastrojejunostomy (SPGJ) improves gastric-outlet obstruction outcomes, yet its biomechanical basis and geometric optimization remain unclear. Patient computed tomography (CT) data were used to reconstruct realistic SPGJ models. Computational fluid dynamics combined with a discrete phase model quantified velocity, wall pressure, particle-retention time, and velocity under systematic variations of partitioning position (distal, mid, and proximal), partitioning angle (5°, 15°, and 25°; left- or right-sided), and incision angle (60°, 75°, and 90°). Distal partitioning produced the lowest pressure drop and fastest emptying, whereas proximal partitioning channeled high-speed flow toward the pylorus and prolonged retention. A ∼15° partitioning angle balanced flow restriction and clearance; extreme unilateral angles either increased particle stasis (left-side) or slowed emptying despite reduced reflux (right-side). A vertical incision (90°) further decreased pressure losses and shortened mean retention relative to oblique cuts. SPGJ biomechanics are highly geometry-sensitive. Distal placement, a 15° partitioning angle, and a near-vertical incision collectively optimize flow, reduce lesion contact, and accelerate gastric emptying, providing quantitative guidance for patient-specific SPGJ design.

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Publication Details

Journal
Annals of the New York Academy of Sciences
Published
2025-10-22
DOI
https://doi.org/10.1111/nyas.70104
Primary Topic
Esophageal and GI Pathology
Type
article
Field-Weighted Citation Impact
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article

Biomechanical Impact of Partitioning Position and Angle on Post‐SPGJ Gastric Emptying

Qiuliang Li, Haiqiao Zhang, Xia Ye, Jun Zhang et al.
Annals of the New York Academy of Sciences
Esophageal and GI Pathology
article

Biomechanical Impact of Partitioning Position and Angle on Post‐SPGJ Gastric Emptying

Qiuliang Li, Haiqiao Zhang, Xia Ye, Jun Zhang, Fengyan Xu, Zhi Zheng, Zhenmin Fan
article en

Abstract

Stomach-partitioning gastrojejunostomy (SPGJ) improves gastric-outlet obstruction outcomes, yet its biomechanical basis and geometric optimization remain unclear. Patient computed tomography (CT) data were used to reconstruct realistic SPGJ models. Computational fluid dynamics combined with a discrete phase model quantified velocity, wall pressure, particle-retention time, and velocity under systematic variations of partitioning position (distal, mid, and proximal), partitioning angle (5°, 15°, and 25°; left- or right-sided), and incision angle (60°, 75°, and 90°). Distal partitioning produced the lowest pressure drop and fastest emptying, whereas proximal partitioning channeled high-speed flow toward the pylorus and prolonged retention. A ∼15° partitioning angle balanced flow restriction and clearance; extreme unilateral angles either increased particle stasis (left-side) or slowed emptying despite reduced reflux (right-side). A vertical incision (90°) further decreased pressure losses and shortened mean retention relative to oblique cuts. SPGJ biomechanics are highly geometry-sensitive. Distal placement, a 15° partitioning angle, and a near-vertical incision collectively optimize flow, reduce lesion contact, and accelerate gastric emptying, providing quantitative guidance for patient-specific SPGJ design.

Annals of the New York Academy of SciencesVol. 1554(1)
Capital Medical University (CN), Jiangsu University of Technology (CN), Beijing Friendship Hospital (CN)
National Natural Science Foundation of China, Beijing Municipal Administration of Hospitals
Openalex Percentile: Top 53%
Esophageal and GI Pathology
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