Developing and optimizing a biocompatible tauopathy model using extracellular vesicle-mediated gene delivery
These findings demonstrate that EVs can serve as a robust and biocompatible platform for tau gene delivery, providing a promising alternative to traditional transfection strategies for generating physiologically relevant tauopathy models.
Authors
- Kristen Dellinger (ORCID: https://orcid.org/0000-0001-8193-7564)
- Samaneh Ghadami (ORCID: https://orcid.org/0009-0007-6232-3285)
Institutions
- North Carolina Agricultural and Technical State University (US)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-10-22
- DOI
- https://doi.org/10.3389/fmed.2025.1672046
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- National Institutes of Health
- National Institute of General Medical Sciences
- Division of Electrical, Communications and Cyber Systems