Associations of polyunsaturated fatty acids and genetic predisposition with cardiovascular risk among hypertensive adults
Despite the general cardiovascular benefits of PUFAs, a higher N6FA/N3FA ratio was associated with an elevated risk of CVD in hypertensive participants. The benefits of PUFAs are greater in those with lower genetic CVD risk. This emphasizes the need to consider N6FA/N3FA balance and genetic predisposition when assessing health impact of PUFAs on CVD.
Authors
- Jindi Li (ORCID: https://orcid.org/0000-0002-5743-6046)
- Yang Peng (ORCID: https://orcid.org/0000-0002-4146-8369)
- Hao Chen (ORCID: https://orcid.org/0000-0003-3666-2033)
- Yunfeng Zou (ORCID: https://orcid.org/0000-0002-8819-1117)
- Yubo Zhang (ORCID: https://orcid.org/0000-0001-8840-9422)
- Quanhong Chen
- Shaohui Liu (ORCID: https://orcid.org/0009-0000-1202-3777)
- Cuihua Nong
Institutions
- Guangxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-10-22
- DOI
- https://doi.org/10.3389/fnut.2025.1623962
- Citations
- 1
- Primary Topic
- Fatty Acid Research and Health
- Type
- article
- Field-Weighted Citation Impact
- 1.12
Funders
- National Natural Science Foundation of China