The Efficacy of Single Dose Linaclotide in Polyethylene Glycol-Based Bowel Preparation
Linaclotide used as a single dose adjunct to bowel prep before colonoscopy increased ADR and PDR. Adequate prep was higher with linaclotide in patients with diagnosed constipation. Linaclotide also decreased the odds of abdominal pain, bloating, and sleep disturbances.
Authors
- Kyle S. Liu (ORCID: https://orcid.org/0000-0003-3747-4421)
- Colby Adamson
- Manuel Garza
- Daryl Ramai
- Andrew Han (ORCID: https://orcid.org/0000-0002-9283-3725)
- Eric Smith (ORCID: https://orcid.org/0000-0003-1127-8537)
- Vincent Nguyen (ORCID: https://orcid.org/0000-0002-9776-6242)
- Bryce Bushe
- Yizhong Wu
- Douglas G. Adler
- Alexander Grieme
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- The University of Texas at San Antonio Health Science Center (US)
- Washington University in St. Louis (US)
- Porter Adventist Hospital (US)
- Texas A&M Health Science Center (US)
- St. David's Round Rock Medical Center (US)
- Texas A&M University (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Journal of Clinical Gastroenterology
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1097/mcg.0000000000002267
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 0.00