Tumours might be sensitized to immune therapy by COVID mRNA vaccines

Commercially available mRNA vaccines against COVID have been shown to train patients’ immune systems to kill cancer cells. Combining these vaccines with standard-of-care immune therapy overwhelms tumour defences and is associated with improved survival, both in animal models and in large cohorts of people with cancer. COVID vaccines enhance the antitumour response of immunotherapies and result in increased patient survival.

Publication Details

Journal
Nature
Published
2025-10-22
DOI
https://doi.org/10.1038/d41586-025-03411-y
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00
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article

Tumours might be sensitized to immune therapy by COVID mRNA vaccines

Nature
Cancer Immunotherapy and Biomarkers
article

Tumours might be sensitized to immune therapy by COVID mRNA vaccines

article en

Abstract

Commercially available mRNA vaccines against COVID have been shown to train patients’ immune systems to kill cancer cells. Combining these vaccines with standard-of-care immune therapy overwhelms tumour defences and is associated with improved survival, both in animal models and in large cohorts of people with cancer. COVID vaccines enhance the antitumour response of immunotherapies and result in increased patient survival.

Nature
Openalex Percentile: Top 60%
Cancer Immunotherapy and Biomarkers
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Tumours might be sensitized to immune therapy by COVID mRNA vaccines · Nature (2025) | TGRS Research Map | TGRS