Linezolid-resistant and vancomycin-resistant <i>Enterococcus faecium</i> urinary isolate in a pediatric B-ALL patient

This case underscores the diagnostic challenges in detecting emerging linezolid resistance in <i>E. faecium</i>, particularly in immunocompromised patients. Accurate, timely susceptibility testing and improved access to confirmatory or molecular diagnostics are essential to guide therapy for VRE where linezolid remains one of the few viable therapeutic options.

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Publication Details

Journal
ASM Case Reports
Published
2025-10-22
DOI
https://doi.org/10.1128/asmcr.00085-25
Primary Topic
Antimicrobial Resistance in Staphylococcus
Type
article
Field-Weighted Citation Impact
0.00
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article

Linezolid-resistant and vancomycin-resistant Enterococcus faecium urinary isolate in a pediatric B-ALL patient

Alaric W. D’Souza, Tanvi Sharma, Emma Seevak
ASM Case Reports
Antimicrobial Resistance in Staphylococcus
article

Linezolid-resistant and vancomycin-resistant Enterococcus faecium urinary isolate in a pediatric B-ALL patient

Alaric W. D’Souza, Tanvi Sharma, Emma Seevak
article en

Abstract

This case underscores the diagnostic challenges in detecting emerging linezolid resistance in <i>E. faecium</i>, particularly in immunocompromised patients. Accurate, timely susceptibility testing and improved access to confirmatory or molecular diagnostics are essential to guide therapy for VRE where linezolid remains one of the few viable therapeutic options.

ASM Case ReportsVol. 2(1)
Boston Children's Hospital (US), Harvard University (US), Boston Children's Museum (US)
Openalex Percentile: Top 64%
Antimicrobial Resistance in Staphylococcus
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