Rac3 promotes proliferation and invasion of endometrial cancer through the AKT/mTOR signalling pathway
Knockdown of Rac3 may inhibit the occurrence and development of EC, which is related to its inhibition of AKT2, AKT3 and mTOR. This discovery provides a theoretical basis for clinical screening of biomarkers for EC and the development of potential therapeutic targets.
Authors
- Xinxin Hu
- Ruyin Lin
- Liangyu Zhou (ORCID: https://orcid.org/0009-0009-6163-0229)
Institutions
- Fujian Medical University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Journal of Obstetrics and Gynaecology
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1080/01443615.2025.2574324
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 0.00