Implications of computed tomography reconstruction algorithms on coronary atheroma composition: A head-to-head comparison with multimodality near-infrared spectroscopy intravascular ultrasound imaging
CTA reconstruction parameters influence plaque composition analysis. The combination of an intermediate-strength IR, thin slice thickness, and fixed HU cutoffs yields the most accurate tissue characterization compared to NIRS-IVUS as the reference standard.
Authors
- James Moon (ORCID: https://orcid.org/0000-0001-8071-1491)
- Jouke Dijkstra (ORCID: https://orcid.org/0000-0002-8666-3731)
- Anantharaman Ramasamy (ORCID: https://orcid.org/0000-0003-1304-8305)
- Nathan Angelo Lecaros Yap (ORCID: https://orcid.org/0000-0001-6294-5796)
- Ryo Torii (ORCID: https://orcid.org/0000-0001-9479-8719)
- Johan H. C. Reiber (ORCID: https://orcid.org/0000-0002-0387-6417)
- İbrahi̇m Hali̇l Tanboğa (ORCID: https://orcid.org/0000-0003-4546-9227)
- Francesca Pugliese (ORCID: https://orcid.org/0000-0001-7497-6266)
- Christos V. Bourantas (ORCID: https://orcid.org/0000-0001-5319-1064)
- Andreas Baumbach (ORCID: https://orcid.org/0000-0001-7707-2254)
- Anthony Mathur (ORCID: https://orcid.org/0000-0001-7941-9653)
- Patrick W. Serruys (ORCID: https://orcid.org/0000-0002-9636-1104)
- Alexander Broersen (ORCID: https://orcid.org/0000-0003-4314-1156)
- S. Kyriakou
- Pieter Kitslaar (ORCID: https://orcid.org/0000-0003-3453-2841)
- Amear Mohammed
- Xingwei He
- Mick Ozkor
Institutions
- Queen Mary University of London (GB)
- Ollscoil na Gaillimhe – University of Galway (IE)
- Barts Health NHS Trust (GB)
- Leiden University Medical Center (NL)
- İstanbul Nişantaşı Üniversitesi (TR)
- Centre for Medical Systems Biology (NL)
- Lung Institute (US)
- William Harvey Research Institute (GB)
- University College London (GB)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of cardiovascular computed tomography
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1016/j.jcct.2025.10.009
- Citations
- 1
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- National Institute for Health and Care Research
- British Heart Foundation
- University College London
- Rosetrees Trust