Exploring the therapeutic role of thiabendazole in lung adenocarcinoma via network pharmacology and single-cell analysis

Thiabendazole demonstrates promising anticancer potential in LUAD, influencing key genes and immune pathways. It may serve as an effective therapeutic agent targeting both cancer cells and the tumor microenvironment.

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Publication Details

Journal
Translational Oncology
Published
2025-10-22
DOI
https://doi.org/10.1016/j.tranon.2025.102548
Primary Topic
Histone Deacetylase Inhibitors Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring the therapeutic role of thiabendazole in lung adenocarcinoma via network pharmacology and single-cell analysis

Chunlin Ye, Wanghong Qi, Guoqiu Xu, Xiancong Liu et al.
Translational Oncology
Histone Deacetylase Inhibitors Research
article

Exploring the therapeutic role of thiabendazole in lung adenocarcinoma via network pharmacology and single-cell analysis

Chunlin Ye, Wanghong Qi, Guoqiu Xu, Xiancong Liu, Lang Tang
article en

Abstract

Thiabendazole demonstrates promising anticancer potential in LUAD, influencing key genes and immune pathways. It may serve as an effective therapeutic agent targeting both cancer cells and the tumor microenvironment.

Translational OncologyVol. 62
Nanchang University (CN), First Affiliated Hospital of Nanchang University (CN)
Openalex Percentile: Top 73%
Histone Deacetylase Inhibitors Research
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Exploring the therapeutic role of thiabendazole in lung adenocarcinoma via network pharmacology and single-cell analysis — Chunlin Ye, Wanghong Qi, et al. · Translational Oncology (2025) | TGRS Research Map | TGRS