Investigating the adjuvant activity of the proline-rich antimicrobial lipopeptide C12-PRP against antimicrobial-resistant veterinary bacterial isolates
We demonstrated the synergistic ability of C<sub>12</sub>-PRP to enhance antibiotic activity and reduce the virulence of the veterinary E. coli isolates, strengthening the potential promise of this adjuvant candidate as a therapeutic agent for multidrug-resistant bacteria.
Authors
- Dawn White (ORCID: https://orcid.org/0009-0007-3150-7436)
- Ayush Kumar (ORCID: https://orcid.org/0000-0001-6395-7932)
- Bala Kishan Gorityala
- Rajeswari Mani
- Soumya Deo
- Frank Schweizer (ORCID: https://orcid.org/0000-0001-8697-5519)
- Aimeen Sharoze
- Meerim Esenbekova
Institutions
- St. John’s Health Sciences Centre (CA)
- Newfoundland and Labrador Centre for Applied Health Research (CA)
- University of Manitoba (CA)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1016/j.jgar.2025.10.015
- Primary Topic
- Antimicrobial Peptides and Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00