A reappraisal of carbapenems dosing in febrile neutropenic patients
Standard carbapenem dosing with 0.5-h infusions may lead to suboptimal exposure in FN patients. Prolonging the infusion duration is an effective strategy to improve PTA and optimize efficacy.
Authors
- R J Ling (ORCID: https://orcid.org/0000-0002-9366-3318)
- Yaojie Chen (ORCID: https://orcid.org/0009-0003-6351-5618)
- Xuben Yu (ORCID: https://orcid.org/0000-0003-1897-4519)
- Xun Zhang (ORCID: https://orcid.org/0000-0003-3586-9921)
- Haina Zhang (ORCID: https://orcid.org/0000-0003-0247-0252)
- Dean Jiang
- Yuhan Zeng
- Shouming Qin (ORCID: https://orcid.org/0000-0002-7411-0101)
- Fu Jing (ORCID: https://orcid.org/0000-0003-1039-0236)
- Min Kong
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1016/j.jgar.2025.10.006
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00