An Experimental Study on the Widely Used Chemotherapeutic Docetaxel: Does It Induce Inflammation, Ischemia, and Neurodegeneration in the Eye, Causing Dry Eye and Blurred Vision in a Real-Life Scenario?
This experimental study demonstrated that DTX induces inflammation and ischemia in ocular tissues, as shown in histopathological sections. Given the rising incidence of cancer and the related use of chemotherapeutics, it is crucial for ophthalmologists to recognize the ocular side effects of drugs like DTX in order to enhance the quality of life for cancer patients undergoing chemotherapy.
Authors
- Bilgin Demir (ORCID: https://orcid.org/0000-0003-4380-9419)
- Buket Demirci (ORCID: https://orcid.org/0000-0002-3442-5061)
- Fadime Kahyaoğlu (ORCID: https://orcid.org/0000-0002-5149-8051)
- Tuna Önal (ORCID: https://orcid.org/0000-0002-3650-4046)
- Sabri Barutça (ORCID: https://orcid.org/0000-0002-1941-0531)
- Ayşe İpek Akyüz Ünsal (ORCID: https://orcid.org/0000-0001-5260-674X)
- Sayime Aydın Eroğlu (ORCID: https://orcid.org/0000-0001-9222-6004)
Institutions
- Manisa Celal Bayar University (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- Bakırçay Üniversitesi
- Adnan Menderes University (TR)
Publication Details
- Journal
- Current Eye Research
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1080/02713683.2025.2575785
- Primary Topic
- Drug-Induced Ocular Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 0.00