Can the icteric index be used instead of total bilirubin in addition to being a preanalytical marker? Icteric index in the laboratory

This is the study with the largest sample size. The sample size is critical in determining a reliable I-index cut-off point. We conclude that I-index should not replace TBil since the NPV was not 100 %; however, it seems reasonable to reflexively add TBil testing in samples where the I-index is above the cut-off value and TBil measurement was not initially planned.

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Publication Details

Journal
Practical Laboratory Medicine
Published
2025-10-22
DOI
https://doi.org/10.1016/j.plabm.2025.e00509
Primary Topic
Clinical Laboratory Practices and Quality Control
Type
article
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article

Can the icteric index be used instead of total bilirubin in addition to being a preanalytical marker? Icteric index in the laboratory

Merve Sena Odabaşı, Zeynep Mine Yalçınkaya Kara
Practical Laboratory Medicine
Clinical Laboratory Practices and Quality Control
article

Can the icteric index be used instead of total bilirubin in addition to being a preanalytical marker? Icteric index in the laboratory

Merve Sena Odabaşı, Zeynep Mine Yalçınkaya Kara
article en

Abstract

This is the study with the largest sample size. The sample size is critical in determining a reliable I-index cut-off point. We conclude that I-index should not replace TBil since the NPV was not 100 %; however, it seems reasonable to reflexively add TBil testing in samples where the I-index is above the cut-off value and TBil measurement was not initially planned.

Practical Laboratory MedicineVol. 47
Şişli Etfal Eğitim ve Araştırma Hastanesi (TR)
Openalex Percentile: Top 62%
Clinical Laboratory Practices and Quality Control
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