The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation
FDE administered after sensitization and during allergen challenge mitigated key asthma features in mice and showed translational potential in human cells, supporting its development as a novel, environmentally derived immunomodulatory strategy.
Authors
- Christoph Müller (ORCID: https://orcid.org/0000-0002-1163-2527)
- Aicha Jeridi (ORCID: https://orcid.org/0000-0002-2120-936X)
- Zeynep Ertüz
- Rabia Ülkü Korkmaz (ORCID: https://orcid.org/0000-0002-2566-5346)
- Erika von Mutius (ORCID: https://orcid.org/0000-0002-8893-4515)
- Janna C. Nawroth (ORCID: https://orcid.org/0000-0003-1898-3968)
- Guilherme Dragunas (ORCID: https://orcid.org/0000-0001-6560-8402)
- Jimmy Omony (ORCID: https://orcid.org/0000-0001-9983-1039)
- Mohab Ragab
- Xiaomei Tan
- Theodore S. Kapellos (ORCID: https://orcid.org/0000-0001-5536-6809)
- Ali Önder Yildirim (ORCID: https://orcid.org/0000-0003-1969-480X)
- Bettina Rankl (ORCID: https://orcid.org/0000-0003-1323-6744)
- Sirui Chen (ORCID: https://orcid.org/0000-0001-9918-6850)
- Markus Klotz
- Soni Shankhwar
- Romina Augustin
Institutions
- Heidelberg University (DE)
- TUM Klinikum (DE)
- Helmholtz Zentrum München (DE)
- Heidelberg University of Education (DE)
- Heidelberg Engineering (Germany) (DE)
- German Center for Lung Research (DE)
- Technical University of Munich (DE)
- Ludwig-Maximilians-Universität München (DE)
- Heidelberg University (US)
Publication Details
- Journal
- Allergy
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1111/all.70121
- Citations
- 1
- Primary Topic
- Pediatric health and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.52