Rapid oxygen release from stored red blood cells can be preserved for longer with refined additive solutions
Over 56 days, SOLX- and PAGGSM-stored RBCs demonstrated faster oxygen release kinetics than SAGM, as measured directly and by the flow-cytometric surrogate. Additionally, SOLX-stored RBCs maintained better ATP levels and hemolysis compliance.
Authors
- Peter A. Smethurst (ORCID: https://orcid.org/0000-0001-6459-1637)
- John R. Hess (ORCID: https://orcid.org/0000-0001-8596-4420)
- Julija Rabcuka (ORCID: https://orcid.org/0000-0002-2367-4636)
- Pawel Swietach (ORCID: https://orcid.org/0000-0002-9945-9473)
- Majid Zia
- Athinoula Meli (ORCID: https://orcid.org/0000-0003-1854-747X)
- Rebecca A. Cardigan (ORCID: https://orcid.org/0000-0001-6823-8937)
- Jennifer Jolley
- Azhar I. Mohamudally
Institutions
- NHS Blood and Transplant (GB)
- University of Washington (US)
- University of Cambridge (GB)
- University of Oxford (GB)
- Data Sciences International (United States) (US)
Publication Details
- Journal
- Transfusion
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1111/trf.18452
- Primary Topic
- Erythrocyte Function and Pathophysiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- NHS Blood and Transplant