Association between hot spring residency and dry eye disease: a crossover gene–environment interaction (GxE) study in Taiwan
We identified hot-spring exposure as a modifiable risk in the PRS-predicted GxE context of DED.
Authors
- Chungsying Lu (ORCID: https://orcid.org/0000-0002-9205-457X)
- Ai‐Ru Hsieh
- He-Jhen Dai
- Pin-Hsuan Chiang
- Wei Chiu
- Kao-Jung Chang (ORCID: https://orcid.org/0000-0002-2238-7387)
- Yi‐Cheng Chen
- Yu‐Chun Chen (ORCID: https://orcid.org/0000-0002-4124-1949)
- Hsin-Yu Wu
- Yu‐Tien Hsu (ORCID: https://orcid.org/0000-0001-6384-9878)
- Chih‐Chien Hsu (ORCID: https://orcid.org/0000-0003-2354-2999)
- Shih-Hwa Chiou (ORCID: https://orcid.org/0000-0002-2481-5357)
- Yu‐Hsiang Chen (ORCID: https://orcid.org/0000-0002-5598-4129)
- Han-Ying Tsai
- Ying‐Chu Lin (ORCID: https://orcid.org/0000-0002-2499-8632)
- Yi-Ping Yang
- C.-C. Wang
- Chih-Hung Hsu
- Yuan-Chih Wen
Institutions
- Zhejiang International Studies University (CN)
- Tamkang University (TW)
- Harvard University (US)
- National Yang Ming Chiao Tung University (TW)
- Taipei Veterans General Hospital (TW)
- Taichung Veterans General Hospital (TW)
- Women's Hospital, School of Medicine, Zhejiang University (CN)
- Zhejiang University (CN)
- National Taipei University (TW)
Publication Details
- Journal
- Human Genomics
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1186/s40246-025-00824-8
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Taipei Veterans General Hospital
- National Science and Technology Council