Leveraging Entrepreneurship Education in Italy’s Inner Areas: Implications for Regional Planning

This paper examines how place-sensitive, transdisciplinary entrepreneurship education can catalyze inclusive innovation in peripheral regions. Drawing on the Pathways to Innovation and Entrepreneurship initiative—implemented in Southern Italy through a collaboration between the University of Naples Federico II and Cornell Tech with the support of the US Diplomatic Mission to Italy—this study explores the role of universities as active agents in regional innovation ecosystems. Adopting an action research methodology across inner and peri-urban territories, the initiative combined transdisciplinary learning, international knowledge exchange, and applied innovation to support regional planning. Findings highlight three interdependent causal pathways: (1) experiental learning and the development of transversal competencies, (2) network formation across scales, and (3) context-sensitive innovation practices. The results show how a locally embedded yet globally networked approach contributes to innovation capacity building of peripheral regions, aligning global knowledge flows with territorial strengths. The paper concludes with implications for embedding EE into regional innovation strategies, fostering diverse network management, and promoting sustainable, place-based development in left-behind places.