Impact of clinical factors and season on inflammatory cytokines in biologic-treated and untreated asthma
In moderate-to-severe asthma, multiple clinical features and season are associated with cytokine levels and might impact inference from proteomics studies. Smoking and BMI are the key proinflammatory factors in biologics-treated and untreated patients.
Authors
- Georg Hahn
- Njira Lucia Lugogo (ORCID: https://orcid.org/0000-0002-0235-7105)
- Javier Cabrera-Pérez (ORCID: https://orcid.org/0000-0002-5408-3820)
- Steven A. Carr (ORCID: https://orcid.org/0000-0002-7203-4299)
- Kailey Brodeur
- Ayobami Akenroye (ORCID: https://orcid.org/0000-0002-1909-1470)
- Pui Y. Lee (ORCID: https://orcid.org/0000-0002-5779-4193)
- Tanawin Nopsopon (ORCID: https://orcid.org/0000-0003-0428-973X)
- Evan E. Hsu
- Scott T. Weiss
- Courtney E LeSon
Institutions
- Broad Institute (US)
- Brigham and Women's Hospital (US)
- Boston Children's Hospital (US)
- Harvard University (US)
- University of Michigan (US)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1186/s12931-025-03373-9
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Massachusetts General Hospital
- Brigham Research Institute