Pathways in the brain, heart and lung influenced by SARS-CoV-2 NSP6 and SARS-CoV-2 regulated miRNAs: an in silico study hinting cancer incidence
This study highlights probable hub genes, drugs targeting them, and associated pathways perturbed by SARS-CoV-2 NSP6. Galectin3 (LGALS3) upregulated in both heart and brain after COVID-19 infection is reported to be influencing all the ten hallmarks of cancer. Our bioinformatics and systems study hints probable effect of COVID-19 infection in cancer incidence and warrants in-depth studies for present scenario of long and recurrent COVID-19.
Authors
- Joydeep Mahata (ORCID: https://orcid.org/0009-0002-2266-5874)
- Suneel Kateriya (ORCID: https://orcid.org/0000-0001-5428-4297)
- Gireesh Anirudhan (ORCID: https://orcid.org/0000-0001-7093-0404)
- Shrabonti Chatterjee (ORCID: https://orcid.org/0009-0001-0669-9268)
Institutions
- Visva-Bharati University (IN)
- Jawaharlal Nehru University (IN)
Publication Details
- Journal
- Cardio-Oncology
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1186/s40959-025-00387-6
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Science and Technology, Ministry of Science and Technology, India
- University Grants Commission