Association of estimated glucose disposition rate with aging acceleration and mortality risk in individuals with cardiovascular-kidney-metabolic syndrome: evidence from two large national population-based studies
In the CKM population, lower eGDR levels may be associated with both AgeAccel and an increased risk of mortality, with AgeAccel potentially mediating the relationship between eGDR and mortality. These findings suggested that eGDR could serve as a potential predictor and intervention target for delaying aging and reducing mortality risk.
Authors
- Y. C. Li
- Mo‐Yao Tan
- Ziyu Li (ORCID: https://orcid.org/0000-0001-5580-4979)
- Bin Niu
- Z. Jiang (ORCID: https://orcid.org/0009-0007-6623-0254)
Institutions
- Chengdu Medical College (CN)
- Integrated Chinese Medicine (China) (HK)
- First Affiliated Hospital of Chengdu Medical College (CN)
- Second Affiliated Hospital of Chengdu University of Traditional Chinese (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1186/s12933-025-02940-0
- Citations
- 1
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 3.49