sRAGE inhibits myocardial ischemia/reperfusion injuries via regulating Treg cells
The study demonstrated that sRAGE protected against myocardial I/R injury by modulating the differentiation of Tregs through upregulation of the JAK2/STAT3-PD-L1 signaling pathway.
Authors
- J. Liu (ORCID: https://orcid.org/0000-0001-6726-3268)
- Caixia Guo (ORCID: https://orcid.org/0000-0003-2313-7731)
- Jing Chang (ORCID: https://orcid.org/0000-0002-2708-3921)
- Hongxia Wang (ORCID: https://orcid.org/0000-0001-8779-1201)
- Lu Chen (ORCID: https://orcid.org/0000-0003-2906-2507)
- Jie Zhang (ORCID: https://orcid.org/0000-0001-6717-4118)
- Xiangjun Zeng (ORCID: https://orcid.org/0000-0002-2553-2244)
- Yu Liu
- Mingcong Huang (ORCID: https://orcid.org/0009-0006-0530-9092)
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
- Beijing YouAn Hospital (CN)
Publication Details
- Journal
- Cell & Bioscience
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1186/s13578-025-01482-y
- Citations
- 1
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 1.32
Funders
- National Natural Science Foundation of China
- Capital Medical University