Depressive disorders in women during the menopausal transition and menopause

The perimenopausal period and menopause are often accompanied by symptoms of depression, since a decrease in estrogen levels causes the decline of reproductive function, emotional disorders, vasomotor symptoms, and genitourinary menopausal syndrome. Since the occurrence of disorders in the psycho-emotional sphere is due to the direct genomic effect of hypoestrogenism, hormone replacement therapy remains the most effective treatment method for vasomotor manifestations. The appointment of antidepressants, neuroleptics, antiepileptic drugs, and anxiolytics allows for a sustained effect in the emotional sphere, improving both the general condition and mental status of women during menopausal transition and menopause.