Differential gene expression profiling and machine learning-based discovery of key genetic markers in VTE and CKD

This study identifies HNRNPA0 and PI4KA as key genes shared between VTE and CKD, providing new insights into their genetic and immunological links. The diagnostic model based on these genes offers a promising tool for CKD prediction and highlights potential targets for future mechanistic and therapeutic investigations.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-10-22
DOI
https://doi.org/10.3389/fimmu.2025.1654673
Primary Topic
Renal and Vascular Pathologies
Type
article
Field-Weighted Citation Impact
0.00
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article

Differential gene expression profiling and machine learning-based discovery of key genetic markers in VTE and CKD

Junjie Kuang, Lin Cai, Hui Li
Frontiers in Immunology
Renal and Vascular Pathologies
article

Differential gene expression profiling and machine learning-based discovery of key genetic markers in VTE and CKD

Junjie Kuang, Lin Cai, Hui Li
article en

Abstract

This study identifies HNRNPA0 and PI4KA as key genes shared between VTE and CKD, providing new insights into their genetic and immunological links. The diagnostic model based on these genes offers a promising tool for CKD prediction and highlights potential targets for future mechanistic and therapeutic investigations.

Frontiers in ImmunologyVol. 16
Huizhou Central People's Hospital (CN)
Openalex Percentile: Top 57%
Renal and Vascular Pathologies
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