Identification of mitochondrial related gene characteristics and potential molecular mechanism of acute otitis media
This study reveals mitochondrial gene expression alterations in AOM, identifying FAM110B, LIG1, and PDK1 as critical genes associated with immune cell infiltration. These findings provide insights into the mitochondrial-immune interplay in AOM pathogenesis.
Authors
- Xiaoyong Ren (ORCID: https://orcid.org/0000-0002-0237-6103)
- Dingjing Zi (ORCID: https://orcid.org/0000-0003-3412-4020)
Institutions
- People 's Liberation Army 451 Hospital (CN)
- Xi'an Medical University (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-10-22
- DOI
- https://doi.org/10.3389/fmolb.2025.1642269
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00