Efficacy and safety of flow diverters in basilar artery aneurysms: a single-center retrospective cohort study

In this retrospective cohort, FD treatment for basilar artery aneurysms was associated with a high rate of complete or near-complete occlusion (86.7%) and a favorable safety profile, as evidenced by the low rate of complications (13.3%, all transient). The clinical outcomes were excellent, with 93.3% of patients achieving an mRS of 0-1. The Tubridge and Pipeline devices demonstrated comparable efficacy and safety outcomes in this study, although the small sample size and non-randomized design preclude definitive conclusions regarding superiority or equivalence. Our findings indicate that rigorous preoperative antiplatelet management and meticulous operative technique are critical for these results. This study supports the consideration of FDs for BAAs in carefully selected patients, but further large-scale, prospective studies are warranted to confirm long-term durability and optimize patient selection.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-10-22
DOI
https://doi.org/10.3389/fneur.2025.1668097
Citations
1
Primary Topic
Intracranial Aneurysms: Treatment and Complications
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article
Field-Weighted Citation Impact
1.39
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article

Efficacy and safety of flow diverters in basilar artery aneurysms: a single-center retrospective cohort study

Chuan Chen, Baoyu Zhang, Ziyuan Huang, Hui Wang et al.
1 citations
Frontiers in Neurology
Intracranial Aneurysms: Treatment and Complications
1.39
article

Efficacy and safety of flow diverters in basilar artery aneurysms: a single-center retrospective cohort study

Chuan Chen, Baoyu Zhang, Ziyuan Huang, Hui Wang, Cong Ling, Yuanjun Hu
article en
1 citations

Abstract

In this retrospective cohort, FD treatment for basilar artery aneurysms was associated with a high rate of complete or near-complete occlusion (86.7%) and a favorable safety profile, as evidenced by the low rate of complications (13.3%, all transient). The clinical outcomes were excellent, with 93.3% of patients achieving an mRS of 0-1. The Tubridge and Pipeline devices demonstrated comparable efficacy and safety outcomes in this study, although the small sample size and non-randomized design preclude definitive conclusions regarding superiority or equivalence. Our findings indicate that rigorous preoperative antiplatelet management and meticulous operative technique are critical for these results. This study supports the consideration of FDs for BAAs in carefully selected patients, but further large-scale, prospective studies are warranted to confirm long-term durability and optimize patient selection.

Frontiers in NeurologyVol. 16
Sun Yat-sen University (CN), Third Affiliated Hospital of Sun Yat-sen University (CN)
Openalex Percentile: Top 15%
Intracranial Aneurysms: Treatment and Complications
1.39
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