Gender Differences in Suicidal and Self-Harming Responses to Esketamine: A Real-World Retrospective Study
Esketamine rapidly improved suicidality and depression in TRD, with preliminary evidence suggesting gender-specific responses, and highlighting the importance of tailored interventions to maximize outcomes. Further research is needed to confirm these differences, explore the long-term effects, and understand the underlying mechanisms.
Authors
- Silvia Testa (ORCID: https://orcid.org/0000-0002-8732-4790)
- Manlio Russo
- Fabiola Raffone (ORCID: https://orcid.org/0000-0002-1818-4237)
- Vassilis Martiadis (ORCID: https://orcid.org/0000-0002-3344-1000)
- Danilo Atripaldi (ORCID: https://orcid.org/0000-0003-3889-3265)
- Domenico De Berardis (ORCID: https://orcid.org/0000-0003-4415-5058)
- Enrico Pessina (ORCID: https://orcid.org/0000-0003-0485-6319)
- Azzurra Martini
- R. Cerlino
- P. Giunnelli
- Carlo Ignazio Cattaneo (ORCID: https://orcid.org/0000-0002-6930-8105)
Institutions
- University of Teramo (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Regione Campania (IT)
- Ospedale degli Infermi (IT)
- Azienda Sanitaria Locale Roma 3 (IT)
Publication Details
- Journal
- Current Neuropharmacology
- Published
- 2025-10-20
- DOI
- https://doi.org/10.2174/011570159x392347250929114024
- Citations
- 11
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 6.36