Association of IL32 Variant rs45499297 with Gingivitis and IL-32 Levels: A Cross-sectional Clinical-bioinformatics Study
Our data show that the rs45499297 gene variant is only associated with gingivitis in the presence of obesity and affects serum cytokine levels. Additionally, we identified the potential involvement of LRH1 in regulating the IL-32 gene expression.
Authors
- Julieta Saraí Becerra‐Ruiz (ORCID: https://orcid.org/0000-0002-9321-0095)
- Fernando Martínez–Esquivias (ORCID: https://orcid.org/0000-0002-5059-3153)
- Luz Andrea Martínez‐Pérez (ORCID: https://orcid.org/0000-0002-9215-4458)
- Sonia Isela Vázquez‐Jiménez (ORCID: https://orcid.org/0000-0001-6239-4998)
- Grecia Denisse González–Sánchez (ORCID: https://orcid.org/0000-0002-4628-8498)
- Ángel Pérez-Reyes (ORCID: https://orcid.org/0000-0001-7185-1636)
- Juan Manuel Guzmán‐Flores (ORCID: https://orcid.org/0000-0002-4673-112X)
Institutions
- Universidad de Guadalajara (MX)
Publication Details
- Journal
- Recent Advances in Inflammation & Allergy Drug Discovery
- Published
- 2025-10-20
- DOI
- https://doi.org/10.2174/0127722708418796251009203141
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00