Women’s thalassemia status and embryo carrier status do not affect pregnancy outcomes after euploid transfers
Thalassemia status and embryo genotype do not appear to adversely affect pregnancy outcomes following euploid embryo transfer. These findings support the transfer of heterozygous carrier embryos and suggest that individualized reproductive counseling and embryo selection strategies can be safely applied in couples at genetic risk of thalassemia undergoing IVF with PGT.
Authors
- Lihui Wei (ORCID: https://orcid.org/0000-0003-1388-6691)
- Ni Tang
- Li Wugao
- Wenjie Huang (ORCID: https://orcid.org/0000-0003-3182-8516)
- Jingjing Li (ORCID: https://orcid.org/0000-0001-8000-7410)
- Li Fan (ORCID: https://orcid.org/0000-0002-6763-0467)
- Zhetao Li (ORCID: https://orcid.org/0000-0002-2036-7673)
- Liuying Nong
Institutions
- Guangxi University of Science and Technology (CN)
- Kunming Medical University (CN)
- Liuzhou Maternal and Child Health Hospital (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-22
- DOI
- https://doi.org/10.3389/fendo.2025.1645590
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00