Efficacy of ceftazidime-avibactam for the treatment of central nervous system infection caused by carbapenem-resistant Klebsiella pneumoniae after neurosurgery
Intravenous CAZ-AVI combined with intracerebroventricular or intrathecal polymyxin B or amikacin demonstrated promising efficacy as a treatment regimen for CRKP-induced CNS infections.
Authors
- Wenkai Cong
- Hongwei Chen (ORCID: https://orcid.org/0000-0002-4079-0153)
- Lin Wang (ORCID: https://orcid.org/0000-0003-2482-7638)
- Shengjie Wang (ORCID: https://orcid.org/0000-0001-8637-7308)
- Zhenhua Bai (ORCID: https://orcid.org/0000-0003-0316-226X)
- Guanghong Qi
Institutions
- Aviation General Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-10-22
- DOI
- https://doi.org/10.3389/fneur.2025.1604045
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00